Ageia PPUs are not recognized by latest PhysX System Software releases, but with a bit of work you will be able to play every game with hardware PhysX acceleration (assuming you have NVIDIA GPU as well), without necessity to reinstall PhysX drivers for each title.
Please note that only certain games (based on PhysX SDK below 2.8.3) are featuring PPU support. Even following this guide, you can't force latest titles like Batman: Arkham City to utilize your PPU.
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